For Warframe, as always a new System/Tileset to explore, a new Warframe as well as a novelty system, it seems like it is mostly what we have each time.
However, DE has hinted a new licence, The bald guy with a hairy face and a wooden desk said on stream that it would probably be in Beta in late 2022 back then(classic ^^), and I fully expect Tennocon to be about that for a good part. It's DE vitrine.