Gauss nuke requires a lot of setup (constant full battery, a lot of energy, priming with heat weapons) and gets cockblocked by most enemies due to Overguard negating heat status.
Saryn nuking the entire room was a thing 10 years ago when she used to nuke level 30 and below missions. She is mainly used as a weapon platform and armor stripping now, her 5-10k spores damage aren't gonna clear any SP difficulty room and they wear off easily without adding any LOS restriction. Miasma gets subsumed 99% of the times.
Equinox needs to kill to stack enough Maim damage (which gets mitigated by armor anyway), and it's so squishy that dies before doing anything.
Most Frames needs to meet some condition in order to perform, wether it is debuffing your enemies, stacking and managing your buffs, building melee combo, respecting LOS, etc, whereas pre-nerf Dante could just do everything from nuke the entire room to giving 60k+ Overguard to the entire squad by simply smashing head on the keyboard.
If you can do all that without any sort of downside that's just blatant, unrestrained power creep.