Same crap every time this is brought up.
Clans are meant to be cooperative so in theory it should be ok as long as everyone is working towards the goal with equal effort. I run a solo clan myself, yes its annoying but there isn't much to be done other than bite the bullet and farm. The drop rate for mutagen sample is awful for how much you need. As much as i want it as something complete in my clan, its better to just farm plat and buy it from the market if you really want it.
It really doesn't matter that the hema is worthless to someone, they should be able to obtain it fairly. I think the only other grind somewhat close to being this bad is for ephemera in arbitrations, every other weapon is fine resource wise imo. I guess sibear might be bad but cryotic is easy to accumulate over time in comparsion to mutagen samples.