6900XT, 23.12.1 drivers, win11.
DX12 - crashes. DX11 - crashes a bit less (and gives A LOT more fps with the same settings... wuut?!), settings: volumetric stuff of all kinds - reduction of it decreased crashes (but still crashes).
So far - new tileset (OFC I want some new stuff) alchemy crashes A LOT, mirror defence just a bit less, assassination almost never crashes and extermination works OK.
Seems there are some relation to a number of effects at once, probably elemental effects, last time game crashed when toxic alchemy bottle/grenade hit an enemy and made THE EFFECT. Seems like elemental heavy melee also caused more crashes, and summonable defence towers. During the quest defence - killed with melee (gram) - crashed, stopped and took ignis, gathered tokens to summon towers - crashed, ok - ignored them too, so finished it after 3 or 4 crashes by staying and power-burning everything.