Same here. Ouch. The only keys that do things are Map, the Zoom and The Mission summary key, telling me all the gems, fish and the scarlet Nexifera I'm going to lost when I have to Alt-F4.
Pretty disappointing to see this bug is six months old. D:
Edit: Well, I WAS pleased to discover that using Alt-F4 to kill the game, when I got back, I had all my resources. So, that's a huge relief.