I generally use Xaku for this, their Vast Untime modded for range (which helps 2 other abilities as well) tends to break everything in a 50m radius, while their kit is still very strong as it scales with enemy level and shreds enemies within' like 15m of them. It's not instant room-clear ability, but it's still very strong if you're running around looking for caches or something similar and don't want to worry about enemies.