No, you dont need a specific frame, no you dont need a specific mission, no you dont need a specific tile, It will work in ANY mission that has respawning enemies (you need to kill enemies for Acolytes to spawn. As long as enemies spawn consistently enough to spawn acolytes every 4-7min its good. Any tileset will work too. Any frame that can control the Acolytes and kill them fast from distance will work. If you're doing survival you only need to worry about sustaining life support, thats it. I've done this farm with Khora, Ivara, Octavia, Nekros, Zephyr, Mesa, Nezha, Protea and could do other frames too if I wanted to.
Many people are calling this a "AFK farm" which only shows that not only they have never done this farm, but even fail to understand the conditions that need to be met for the Acolyte to spawn in the first place. Most people do this kind of farm in Survival missions. You need to 1. sustain life support (Either very high kill rate or using frames with additional loot abilities), 2. Pick up everything so you dont reach loot cap, 3. Kill enough enemies to trigger Acolyte spawns, 4. Be able to control and burst acolytes quickly, 5. Keep your Smeeta alive, 6. Have enough patience or desire to even do that in the first place.
This farm is almost always done in solo, and main reason people that use this method to farm SE is to get Kuva. Why are so many people against me being able to farm 1k kuva per minute as opposed to 500 kuva per minute is beyond me. This method does not trickle into public groups, no one is being forced to do it, theres no griefing involved or anything like that.
So any of you that oppose this method, please tell me why I shouldnt be able to farm with this method and how it affects you, personally. Anyone that will respond and call this method an "AFK farm" I wont reply, thats beyond ignorant, unless I dont know something (I came back to the game after a 2 year break couple months ago, so maybe there are legit AFK farm exploits that im completely unaware of, however if thats the case, then these people should get banned). If you know how to spawn Acolytes without killing enemies, please do tell me.