[The best weapon to use for lvl 100+ enemies 2016 edition?]

Hey guys and girls,

Asking what are the best weapon to use against lvl100+ Corpus, Grineer, and Infested? Thanks for the help.

[Prime weapons]

It's cool. Can regular warframes use Prime weapons? Yes.  "I would hate to craft one of the prime weapons and then not be able to use it." No worries there you can craft any weapon to be use with any frame, prime or non-prime.

[Warframe Builder]

While going through the list of Weapon builds and you click any of them the mod slots appear empty