[Most Powerful warframes lorewise]

Well, I'd say there's a few on my mind.

 

Ash was the patron saint of Orokin assassination, so it's safe to say he was pretty damn strong and good at his job.

 

Atlas was able to redirect a damn meteor spaceship in his Leverian tale.

 

Sevagoth, and by extension the tempestarii, were able to cause havoc and drop a massive corpus installation. 

 

Nova is a manipulator of antimatter.

 

Protea. Oh, Protea, my beloved frame. AND SHE CAN MANIPULATE TIME WHAT-