Secondary Wound - Gain 1 Puncture Status Effect every time you take damage.
Lethargic Shields - Shield recharge delay increased 500%.
Fractured Armor - Casting an ability reduces Armor by 10% for 10s.
Untreatable - Pickups do not heal, and Health Orbs cannot be picked up.
Abbreviated Abilities - Ability Durations reduced by 75%.
Concussive Drain - Taking health damage also consumes 5% of max energy per hit
Exposure Curse - Shields are removed.
Sanguine Syndrome - Every time you take damage, you also suffer a Bleed Status Effect.
Any frame can bypass it:
Framecurse Syndrome - Activating an Ability inflicts 50 damage upon you.
Knifestep Syndrome - Lose 2 Health when moving. Jumping pauses the effect.
Vampyric Syndrome - Lose Health every second. Killing enemies restores Health.
Conductive - Take Electrical damage every few seconds.
Yeah, I think it's safe to say that we still have no end game lol