I understand the motivation but I feel it is a bad idea. Here is why:
There is a whole lot of explanation and character development as to who we are, why we are, and what we are. There is also a lot of character development with lotus, the Queen's, teshin, and ordis that are pretty integral to understanding the setting and experience as a whole.
The only way forward I see if you're going to let them skip all the important stuff (literally) is to produce a series or film that covers all of it. Something they'll have to watch if they wanna skip so that they understand. Animated comic would be a good option. Could probably cover it all in 30 minutes. Aside from learning certain game systems and mechanics, there isn't a whole lot they need out of the quests.
With the way the game is set up, quest missions tend to feel repetitive since for the most part the missions are regular missions with some dialogue added.
What would help, doing down this path or not, would be to streamline all the currencies in the game. Remove "standing" types like quill ostron syndicate Solaris u, Solaris V, tokens etc etc.. and convert it all down to focus. Then as you earn focus points you also earn focus tokens that you can then spend with any and all npc groups. Splitting time among all the different money types is a real strain and progression gate. Buff focus boons, let people spend focus.
Another good idea would be letting us spend mastery. The game tracks how much xp was earned with frames and weapons. Let us spend that xp as a currency for other things. Perhaps spend that with NPCs for ranks.
So, spend mastery (tracked excess xp) for ranks in syndicates, and spend focus for npc goods. Buff focus boons and remove focus caps. Then those same players can advance through actual content at a much higher rate after they skip their quests since skipping quests doesn't auto complete the butt loads of content islands.
Grinding will have way more purpose and utility that way.